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PRB’s widely referenced World Population Data Sheet ( has been produced annually since 1962.This year’s edition provides the latest data on 19 key population, health, and environment indicators for the world, major regions, and more than 200 countries.

Next-generation sequencing success rates varied: more than 80% of the viral genome from the gag to the nef genes could be determined for all sequences from South Africa, 75% of sequences from Mochudi, 60% of sequences from MRC/UVRI Uganda, and 22% of sequences from Rakai.We found a threshold in terms of taxon sampling below which the patchy distribution of missing characters in next-generation sequences has an excess negative impact on the accuracy of HIV-1 phylogeny reconstruction, which is attributable to tree reconstruction artifacts that accumulate when branches in viral trees are long.The large number of PANGEA-HIV sequences provides unprecedented opportunities for evaluating HIV-1 transmission dynamics across sub-Saharan Africa and identifying prevention opportunities.In 2018, there are two Easter public holidays celebrated in the UK.Good Friday is observed across the UK, while Easter Monday is celebrated everywhere except Scotland.*Please refer to this note for Scotland-specific information.